You can’t apply certain filters (such as the Lighting Effects filter) to layers with no pixels. Selecting Fill With (Mode)-Neutral Color in the New Layer dialog box resolves this problem by first filling the layer with a preset, neutral color. This invisible, neutral color is assigned according to the layer’s blending mode. If no effect is applied, filling with a neutral color has no effect on the remaining layers. The Fill With Neutral Color option is not available for layers that use the Normal, Dissolve, Hard Mix, Hue, Saturation, Color, or Luminosity modes.